Skincare
Products that protect and care for our skin.
The Skin
The skin is the largest human organ and is made up of epithelial tissue. This tissue is made up of sheets of cells and covers exterior surfaces, lines internal cavities, and forms some glands within the body. The skin is made up of three main layers: the epidermis, dermis, and hypodermis. Most of our skin is considered thin skin, while the palms of our hands and soles of our feet have thick skin. Overall, skin and its accessories (like hair and sweat glands) make up the integumentary system, which provides bodily protection.
Epidermis
The epidermis is made up of four to five layers of epithelial cells. It is avascular, meaning that this layer contains no blood vessels. Thin skin is made up of 4 layers: the stratum basale, stratum spinosum, stratum granulosum, and stratum corneum. Thick skin contains an extra layer between the stratum granulosum and stratum corneum called the stratum lucidum. All these layers, with the exception of the basale layer are keratinocytes (cells that manufacture and store the protein keratin. Keratin is a intracellular fibrous protein that gives hair, nails, and skin their hardness and water resistant properties. The keratinocytes in the stratum corneum are dead and regularly slough away and are replaced by deeper cells.
Dermis
The dermis may be considered the “core” of the integumentary system (derma- = “skin”), as distinct from the epidermis (epi- = “upon” or “over”) and hypodermis (hypo- = “below”). It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that compose an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts (Figure 5.7).
Papillary Layer: The papillary layer is made of loose, areolar connective tissue, which means the collagen and elastin fibers of this layer form a loose mesh. This superficial layer of the dermis projects into the stratum basale of the epidermis to form finger-like dermal papillae (see Figure 5.7). Within the papillary layer are fibroblasts, a small number of fat cells (adipocytes), and an abundance of small blood vessels. In addition, the papillary layer contains phagocytes, defensive cells that help fight bacteria or other infections that have breached the skin. This layer also contains lymphatic capillaries, nerve fibers, and touch receptors called the Meissner corpuscles.
Hypodermis
The hypodermis (also called the subcutaneous layer or superficial fascia) is a layer directly below the dermis and serves to connect the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for the integument.
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Skincare Products
Cleansers
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Moisturizers
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Deodorants & Antiperspirants
Sweat Glands
When the body becomes warm, sudoriferous glands produce sweat to cool the body. Sweat glands develop from epidermal projections into the dermis and are classified as merocrine glands; that is, the secretions are excreted by exocytosis through a duct without affecting the cells of the gland. There are two types of sweat glands, each secreting slightly different products.
An eccrine sweat gland is type of gland that produces a hypotonic sweat for thermoregulation. These glands are found all over the skin’s surface, but are especially abundant on the palms of the hand, the soles of the feet, and the forehead (Figure 5.14). They are coiled glands lying deep in the dermis, with the duct rising up to a pore on the skin surface, where the sweat is released. This type of sweat, released by exocytosis, is hypotonic and composed mostly of water, with some salt, antibodies, traces of metabolic waste, and dermicidin, an antimicrobial peptide. Eccrine glands are a primary component of thermoregulation in humans and thus help to maintain homeostasis.
An apocrine sweat gland is usually associated with hair follicles in densely hairy areas, such as armpits and genital regions. Apocrine sweat glands are larger than eccrine sweat glands and lie deeper in the dermis, sometimes even reaching the hypodermis, with the duct normally emptying into the hair follicle. In addition to water and salts, apocrine sweat includes organic compounds that make the sweat thicker and subject to bacterial decomposition and subsequent smell. The release of this sweat is under both nervous and hormonal control, and plays a role in the poorly understood human pheromone response. Most commercial antiperspirants use an aluminum-based compound as their primary active ingredient to stop sweat. When the antiperspirant enters the sweat gland duct, the aluminum-based compounds precipitate due to a change in pH and form a physical block in the duct, which prevents sweat from coming out of the pore.
Deodorants & Antiperspirants
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